Correlation of abnormal gonadotropic hormones and lipid fractions in association with anthropometric parameters

Abstract

In this study, the predictive capabilities of newly designed anthropometric indices (a body shape index ABSI, body roundness index BRI and visceral adiposity index VAI) were observed in determination of abnormal gonadotropic hormones (follicle stimulating hormone FSH and Luteinizing hormone LH) along with abnormal lipid profile in 289 females from local area of Lahore. FSH and LH levels were measured by using commercially available kits working on the principle of chemiluminescent micro particle immunoassay (CMIA). The lipid profile (i.e. Total cholesterol TC, Triglyceride TG and High density lipoprotein cholesterol HDL-C) were evaluated by using colorimetric method, while mathematical formula was used for calculation of low density lipoprotein cholesterol LDL-C. The anthropometric indices (ABSI, BRI and VAI) were calculated by using standardized formulas using weight (kg), height (m) and waist circumference (cm). The results revealed that low level of HDL-C is the most lipid abnormality in studied population. The trend of ABSI BRI and VAI were not so different in FSH and LH based groups. Non-significant results and receiver operating characteristic curve analysis showed weak predictive capabilities for abnormal FSH and LH levels. A conclusion can be made from the above data, that ABSI, BRI and VAI are not strong predictors of abnormal gonadotropic hormone level.